Micotil® (tilmicosin injection)

Micotil® is a proven, long-lasting treatment option with a flexible dose range for bovine respiratory disease (BRD) in cattle.

Micotil® is indicated for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica.

Commitment to Safety

Over the last two decades, Elanco has invested significant resources to ensure Micotil’s safe usage, including materials and training for distributors, veterinarians and producers. Among safety elements offered at no charge:

The Simcro® Sekurus® safety syringe, which has patented technology with self-tenting and needle-guard features. The syringe reduces the chance of accidental self-injection and withstands the most challenging environments at feedyards and stocker operations. To date, more than 30,000 have been distributed.

Extensive safety training is offered to more than 1,750 veterinarians and beef producers each year, including how to respond in case of accidental exposure to the product. 

Packaging to further enhance the safety profile, including an outer case that locks the bottle inside. 

Also, Elanco has voluntarily discontinued Micotil 300 Injection 100mL bottle in the U.S. due to a review of data that suggests customers utilizing this presentation have a higher incident rate of accidental human exposures.  

For more information on Micotil safety, please visit our Safe Handling and Use page.

Put the benefits of the flex dose to work in your operation

When dosing to the load average, heavier animals may not receive an adequate treatment. The Micotil Flex dose allows you to better manage on-arrival animal weight and risk variation and also delivers more cost-effective pull-and-treat therapy in the hospital pen.4

Important Product Information 

Learn more about how to properly administer, store and use Micotil. See label for complete use guidelines, including all cautions and warnings. Always read, understand and follow the label and use directions.


Micotil® (tilmicosin injection) is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni, and for the control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica.

See label for complete use information. Before using this product, it is important to read the entire product insert, including the boxed human warning.

  • Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
  • Not for human use. Injection of this drug in humans has been associated with fatalities. Keep out of reach of children. Do not use in automatically powered syringes. Exercise extreme caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice or cold pack to injection site while avoiding direct contact with the skin. Avoid contact with eyes.
  • Always use proper drug handling procedures to avoid accidental self-injection. Consult your veterinarian on the safe handling and use of all injectable products prior to administration.
  • For use in cattle or sheep only. Inject subcutaneously. Injection of this antibiotic has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
  • Do not use in female dairy cattle 20 months of age or older. Use in lactating dairy cattle may cause milk residues.
  • The following adverse reactions have been reported: in cattle: injection site swelling and inflammation, lameness, collapse, anaphylaxis/anaphylactoid reactions, decreased food and water consumption, and death.
  • Micotil has a pre-slaughter withdrawal time of 42 days. 

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